Fourier transform Raman and infrared spectroscopic analysis of novel biliverdin compounds

摘要

The verdin chromophores are members of a class of tetrapyrroles occuring in animals and plants. They are involved in a variety of physiological processes [1]. The biological action of the chromophores is dependent on the structure and conformation of these chromophore molecule. The underlying molecular structure of verdin chromophores is still not sufficiently known, because their crystal structure data are not available. Spectroscopic techniques have successfully been applied as structure analysis methods to these chromophores. Among the spectroscopic techniques that provide detailed information about molecular structure, vibrational spectroscopy is the most appropriate tool to analyse the molecular structure of these chromophores. Several studies have focused on the vibrational spectroscopic analysis of biliverdin dimethyl ester and its isomers [2,3]. The present work describes the Fourier-transform Raman (FT-Raman) and infrared (FT-IR) spectra of five novel biliverdin compounds (see Fig. 1). The effect of molecular structure on molecular vibration of biliverdin compounds is discussed.