Porcine Contagious Pleuropneumonia of the pig is a clearly defined pathologic entity. It is widely distributed and its epidemiologic significance is correlated with industrialization of pig production. Actinobacillus pleuropneumonia is the organisn that causes the disease. The disease impose a heavy economic losses derived from both the mortality of affected animals and the effect upon growth and productivity. Pigs with clinically apparent pleuropneumonia do not grow at their genetic potential due tochronic respiratory disease and consequently their daily gain is reduced and the feed efficiency is badly affected too. Several strategies ha ve been tried in order to control the disease or at least to reduce the severity that it might have in some affected populations. A more economical approach to control of Porcine Contagious Pleuropneumonia is the use of medication in feed for the animals which are at risk in infection. In some farms it is even possible to determine the period of high risk of outbreak in a group or a bam and to implement the administration of medicated feed before the disease breaks. The objetive of the present work was to compare the efficacy of two antimicrobials administered in feed to pigs using a heavy challenge of live Actinobacillus pleuropneumoniae.
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