A thin film analog of the precorneal mucus coating, which is sandwiched between the aqueous tear film and the glycocalyx carrying corneal epithelial surface, is designed. Experimental results are presented on the instability and rupture of thin (approx 100 nm) liquid polydimethylsiloxane (PDMS) films sandwiched between an aqueous medium and a silicon wafer grafted with PDMS "brushes". Lowering of the PDMS-water interfacial tension by a surfactant results in dewetting even of micrometer thick films within a few minutes. The instability appears to be induced by a long range non-classical DLVO force which has the same decay behavior as the nonretarded van der Waals force, but has a magnitude which is about 2 to 3 orders higher. Implications for the breakup of theprecorneal mucus layer and the tear film are briefly discussed.
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机译：设计了一种薄膜粘膜涂层的薄膜，其夹在含水泪膜和携带角膜上皮表面之间的糖蒜酱之间。提出了实验结果，提出了薄（大约100nm）液体聚二甲基硅氧烷（PDMS）膜夹在水性介质和接枝的硅晶片之间的液体聚二甲基硅氧烷（PDMS）薄膜的不稳定性和破裂。通过表面活性剂降低PDMS-水界面张力导致几分钟内脱摩量厚膜即使是脱脂。稳定性似乎由长距离的非古典DLVO力引起，该DLVO力具有与非vAN der WALS力相同的衰减行为，但具有幅度为约2至3个较高的幅度。简要讨论了对Precorneal粘液层和泪膜分解的影响。
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