Population Growth Kinetics of Tetrahymena pyriformis Exposed to Selected Electrophiles

摘要

This study describes the effects of two selected electrophilic chemicals on the population growth kinetics of the freshwater ciliate Tetrahymena pyriformis (strain GL). The two chemicals selected, 3-butyn-2-one and trans-2-nonenal, each have a polarized, alpha, beta-unsaturated moiety, which is associated with the electrophilic mechanism of Michaeltype addition. T.pyriformis populations exposed to both electrophiles exhibited concentration dependent death of the initial inoculum within 1 to 2 h. Three-butyn-2-one which has a low 1-octanol-water partition coefficient (log K_OW = -0.89) exhibited greater toxicity with death observed at 0.068 mg/L. Death was first observed in the more hydrophobic, trans-2-nonenal (log K_OW = 3.16) at 4.21 mg/L. Death was followed by recovery of the population at the growth rates similar to control populations without chemical exposure.