This paper presents experimental and theoretical investigations on the liquid flow in microchannels. Measurements on water flow in microchannels with hydraulic diameter ranging from 50μm to 300μm and Reynolds number ranging from 50 to 1500 were carried out. Experimental results showed that the flow transition does not occur in this range of Reynolds number. Current results also showed that flow characteristics deviated from conventional behaviour predicted by Navier-Stokes equations, when the channel dimensions are below 100μm. Attempts have been made to explain the flow phenomena by employing a slip boundary condition to Navier-Stokes equations. Preliminary results showed that the prediction agrees well with the measurements. The detail explanation will be shown and discussed.
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