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Graph Domain Adaptation for Alignment-Invariant Brain Surface Segmentation

机译:图形域适应对齐 - 不变性脑表面分割

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The varying cortical geometry of the brain creates numerous challenges for its analysis. Recent developments have enabled learning cortical data directly across multiple brain surfaces via graph convolutions. However, current graph learning algorithms fail when brain surface data are misaligned across subjects, thereby requiring to apply a costly alignment procedure in pre-processing. Adversarial training is widely used for unsupervised domain adaptation to improve segmentation performance on target data whose distribution differs from the training source data. In this paper, we exploit this technique to learn surface data across inconsistent graph alignments. This novel approach comprises a segmentator that uses graph convolution layers to enable parcellation across brain surfaces of varying geometry, and a discriminator that predicts the alignment-domain of surfaces from their segmentation. By trying to fool the discriminator, the adversarial training learns an alignment-invariant representation which yields consistent par-cellations for differently-aligned surfaces. Using manually-labeled brain surface from MindBoggle, the largest publicly available dataset of this kind, we demonstrate a 2%-13% improvement in mean Dice over a non-adversarial training strategy, for test brain surfaces with no alignment or aligned on a different reference than source examples.
机译:大脑的不同皮质几何形状为其分析产生了许多挑战。最近的发展通过图表卷积使得在多个脑表面上直接学习皮质数据。然而,当大脑表面数据跨对象未对准时,当前图形学习算法失败,从而需要在预处理中应用昂贵的对准过程。对抗训练广泛用于无监督域适应,以改善分配与训练源数据不同的目标数据上的分割性能。在本文中,我们利用了这种技术来学习跨越图形对齐的曲面数据。这种新方法包括分段器,该分段器使用曲线图卷积层,使得跨不同几何形状的脑表面的围绕,以及预测表面的对准结构域的判别符。通过试图欺骗鉴别者,对抗性培训学习了对齐不变的表示,其为不同排列的表面产生一致的间隔。从Mindboggle使用手动标记的大脑表面,这类最大的公共数据集,我们在非对抗训练策略中展示了平均骰子的2%-13%,用于测试脑表面,没有对齐或在不同的情况下对齐引用比源示例。

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