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A Coplanar Waveguide System for Drug Delivery Mediated by Nanoelectroporation: an Experimental and Numerical Study

机译:纳米电镀介导的药物递送的共面波导系统:实验性和数值研究

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Nanosecond pulsed electric fields (nsPEFs) can interact with lipid vesicles, that are primary drug delivery nanocarriers activated by external signals. In this work, authors propose a new setup of an experimental bench suitable for nsPEFs exposure of liposome nanosystems, compliant with the wideband requirements for nanosecond pulses. A multiphysics modelling able to predict liposome poration is proposed to define the characteristics of signals to be used in experiments.
机译:纳秒脉冲电场(NPEFS)可以与脂质囊泡相互作用,即由外部信号激活的主要药物递送纳米载体。在这项工作中,作者提出了一种适用于NPOSEMS纳米系统的NPPEFS暴露的实验性替补型的新设置,符合纳秒脉冲的宽带要求。提出了一种能够预测脂质体积的多体造型,以定义在实验中使用的信号的特性。

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