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Novel thin film cuff electrode for neural stimulation

机译:用于神经刺激的新型薄膜袖带电极

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摘要

One approach to reestablish disabled functions or to treat chronic diseases of patients is the electrical stimulation of nerves. This requires, in addition to special stimulator electronics, a dedicated electrode in close contact with the specific nerve. We present a new type of spiral self-sizing nerve cuff electrode capable of selective activating specific regions of a nerve trunk. The cuff consists of eight active contacts produced by technologies taken from microelectronics. A platinum metallization for contacts and connection wires was made on a sandwich flexible bi-layer polyimide foil substrate embedded in a biocompatible insulation (silicone). With such a design wrap thickness under 40μm were obtained. The spiral-like arrangement of the cuff placed around the nerve trunk allows a tight cuff to nerve contact without penetrating the nerve. The miniaturized active contact area along with the increased number of electrodes imply a highly spatial selectivity together with the need for a high charge transfer. Therefore we are focusing our research on alternative coatings like iridium oxide which promises to enable high current densities. The electrode's design, requirements and production are described.
机译:恢复神经功能或治疗患者慢性疾病的一种方法是电刺激神经。除了特殊的刺激器电子设备,这还需要与特定神经紧密接触的专用电极。我们提出了一种新型的螺旋自定尺寸神经袖带电极,该电极能够选择性激活神经干的特定区域。袖带由八个活动触点组成,这些触点由微电子技术生产。在嵌入生物相容性绝缘材料(有机硅)的夹层柔性双层聚酰亚胺箔基板上,制成用于触点和连接线的铂金属化层。通过这样的设计,可获得小于40μm的厚度。围绕神经干放置的袖带呈螺旋状排列,可以使袖带紧密接触神经,而不会穿透神经。活性接触面积的最小化以及电极数量的增加暗示了高度的空间选择性以及对高电荷转移的需求。因此,我们将研究重点放在可实现高电流密度的替代涂层上,例如氧化铱。描述了电极的设计,要求和生产。

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