Effect of transdermal energy on drug's permeability flux

摘要

The effect of transdermal energy on the fluxes of TetracainiHydrochlordum (TH) and Naproxenum is studied to explore the low voltageelectroporative technique. The results show that: (1) the drug'stransdermal energy will create a saturation; (2) the F/E value declinesas time extends; and (3) the effect of electroporation is concerned withenergy and the drug's characteristics