The interaction of the europium complex with human serum albumin

摘要

Investigation of proteins interactions with luminescent europium complex is interesting for the practical task of sensitiveprotein detection, as well as to study fundamental problems of peptide-lanthanide interplay. Presented work is devoted toexamine the spectroscopic properties of europium complex (europium trinitrate (2,2'-bipyridyl-6,6'-dikarbonilazandiil)tetrakis (methylene) phosphonate) and to study its interaction with human serum albumin usingvarious spectroscopic techniques. This complex has unique optical ability such as high values of the phosphorescenceintensity in aqueous solutions, which exceeds the intensity of many other known coordination complexes of rare earthelements.