Photodynamic Therapy (PDT) is an alternative to surfaces decontamination which is based on the interaction between anon-toxic photosensitizer (PS) and a light source suitable for the formation of reactive oxygen species. The objective ofthis work was to test two new patented devices, the “Photodynamic Inactivation Device” (PID) (MU-BR20.2017.002297-3) and “Ultrasonic Photodynamic Inactivation Device" (UPID) (MU-BR 20.2018.009356-3), in the photodynamicinactivation (PDI) on contaminated solid surfaces. This device contains low cost light emitting diodes (LEDs) and wasbuilt on structures to improve light distribution. This, a low-cost alternative was tested in different microorganisms presenton the human microbiota: Staphylococcus aureus, Streptococcus mutans, Escherichia coli and Candida albicans. Resultsshowed that PID caused a significant reduction (p<0.05) of the microbial charge stuck in the orthodontic instruments andthe UPID promoted significant reduction (p<0.001) of the microbial in the acrylic plates and titanium disk when comparedwith the positive control. The new device promoted an effective microbial inhibition on the surfaces tested and, thus,making new studies possible. The perspective is that this new device may be a low-cost and non-toxic alternative to thedisinfection of biomedical devices, non-critical instruments and for use in food industry.
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