Modelling and Analysis of Nanosphere Biosensor

摘要

Nano-sphere biosensor is an effective biosensing device used in the applications such as detection of various diseases, safety monitoring of food, diagnosis of cancer. In this work the modeling and analysis of nanosphere biosensor is carried out at a wavelength of 620nm. Finite element method is used for modeling. Light confinement of the biosensor is analyzed along with the analyte concentration and density of transient captured target molecule in analytical method. The SNR of 1.78691 is obtained for 1 × 10¹¹ cm⁻² receptor density, the lower value of signal to noise ratio indicates that the device simulated provides good response to the biomolecules under detection.