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Modern Life Makes Children Sick

机译:现代生活使孩子生病

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摘要

In the past 60 years, the prevalences of asthma and allergy among children has increased all around the world. Neither genetic nor outdoor environmental factors can explain this increase. We performed a cross-sectional study of 7366 children in Tianjin, China, on associations of home environment and life styles with asthma and allergy. The prevalences of diagnosed asthma, rhinitis and eczema among 0-8 year-old children in the Tianjin area were 4%, 9% and 39%. For asthma and allergy, the population attributable fraction (PAF) due to modern floors and wall coverings (i.e. laminated wooden floors and painted walls compared to tile floors and lime-coated walls) was 23%. Window condensation in winter and air conditioner use in summer, which are proxies of less ventilation, accounted for 4%-18% of rhinitis and eczema. Caesarean delivery accounted for 8%-12% of rhinitis and eczema symptoms. We developed a modern life index from appropriate home characteristics and lifestyle and food consumption habits and found it to have a clear dose-response relationship with asthma and allergy in Tianjin children. It indicated that a "modern" home environment together with a modern lifestyle was associated with increased prevalence of asthma and allergies among children.
机译:在过去的60年中,儿童哮喘和过敏症的患病率在全世界范围内均呈上升趋势。遗传因素和室外环境因素都不能解释这一增加。我们对中国天津市7366名儿童的家庭环境和生活方式与哮喘和过敏的关联性进行了横断面研究。天津地区0-8岁儿童的确诊为哮喘,鼻炎和湿疹的患病率分别为4%,9%和39%。对于哮喘和过敏症,现代地板和墙壁覆盖物(即,层压木地板和粉刷墙壁与瓷砖地板和石灰涂层墙壁相比)造成的人口归因分数(PAF)为23%。冬季窗户结露,夏季使用空调,这是通风不良的代表,占鼻炎和湿疹的4%-18%。剖腹产占鼻炎和湿疹症状的8%-12%。我们通过适当的家庭特征,生活方式和饮食习惯建立了现代生活指数,发现该指数与天津儿童的哮喘和过敏有明显的剂量反应关系。它表明,“现代”家庭环境与现代生活方式共同导致哮喘患病率增加和儿童过敏。

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