【24h】

DNASynth: A software application to optimization of artificial gene synthesis

机译:DNASynth:优化人工基因合成的软件应用程序

获取原文

摘要

DNASynth is a client-server software application in which the client runs in a web browser. The aim of this program is to support and optimize process of artificial gene synthesizing using Ligase Chain Reaction. Thanks to LCR it is possible to obtain DNA strand coding defined by user peptide. The DNA sequence is calculated by optimization algorithm that consider optimal codon usage, minimal energy of secondary structures and minimal number of required LCR. Additionally absence of sequences characteristic for defined by user set of restriction enzymes is guaranteed. The presented software was tested on synthetic and real data.
机译:DNASynth是一个客户端服务器软件应用程序,其中客户端在Web浏览器中运行。该程序的目的是支持和优化使用连接酶链反应合成人工基因的过程。由于LCR,可以获得由用户肽定义的DNA链编码。通过优化算法计算DNA序列,该算法考虑了最佳密码子使用,最小的二级结构能量和最少的所需LCR数量。另外,保证没有用户限制酶组定义的特征性序列。所提供的软件已在合成数据和真实数据上进行了测试。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号