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Assessment of vascular remodeling therapy in patients with liver metastasis with 3D dynamic contrast-enhanced ultrasound

机译:3D动态对比增强超声对肝转移患者血管重构治疗的评估

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Vascular remodeling agents that can enhance the effects of chemotherapy have gained significant attention. However, timing and dosing of combinatory treatment regimens requires longitudinal biomarkers to optimize regimens on a patient-by-patient basis. 3D dynamic contrast-enhanced ultrasound (DCE-US) has been proposed as an inexpensive bedside tool to longitudinally guide dosing and scheduling of combined treatments. The purpose of this pilot study was to demonstrate the feasibility of using 3D DCE-US to identify patients with remodeled vasculature before secondary chemotherapy delivery.
机译:可以增强化疗效果的血管重塑剂已引起广泛关注。然而,组合治疗方案的时间安排和剂量要求纵向生物标记物以逐个患者为基础优化方案。 3D动态对比增强超声(DCE-US)已被建议作为一种廉价的床头工具,可纵向指导联合治疗的剂量和时间表。这项初步研究的目的是证明在二次化疗之前使用3D DCE-US识别脉管系统重构的患者的可行性。

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