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Assessment of vascular remodeling therapy in patients with liver metastasis with 3D dynamic contrast-enhanced ultrasound

机译:3D动态对比增强超声肝转移患者血管重塑治疗评估

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摘要

Vascular remodeling agents that can enhance the effects of chemotherapy have gained significant attention. However, timing and dosing of combinatory treatment regimens requires longitudinal biomarkers to optimize regimens on a patient-by-patient basis. 3D dynamic contrast-enhanced ultrasound (DCE-US) has been proposed as an inexpensive bedside tool to longitudinally guide dosing and scheduling of combined treatments. The purpose of this pilot study was to demonstrate the feasibility of using 3D DCE-US to identify patients with remodeled vasculature before secondary chemotherapy delivery.
机译:可以增强化疗效果的血管重塑剂获得了显着的关注。然而,组合治疗方案的时序和给药需要纵向生物标志物,以优化患者患者的基础上的方案。 3D动态对比度增强超声(DCE-US)被提出为符合纵向指导给药和组合治疗的调度的廉价床头柜。该试点研究的目的是展示使用3D DCE-US的可行性来鉴定次级化疗递送前识别重塑脉管系统的患者。

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