The Estimation of a Gold Nanoparticles Distribution Using the Evanescent Electric Field in Gold Nanoparticles Filled Surface Plasmon Resonance Biosensing

摘要

The estimation of a gold nanoparticles (AuNPs) distribution using the evanescent electric field in AuNPs filled surface plasmon resonance (SPR) biosensing is proposed here. The average evanescent electric fields in the 2-dimensional (2D) sensing structure containing thin gold and saline layers are determined. The location of AuNPs from the gold/saline interface has a great influence on the shift of the evanescent field profile. The results also indicate that higher number of AuNPs with preferably uniform distribution provides very strong profile shift. The shifts observed in most profiles are well correlated with those of the surface plasmon resonance (SPR) curves.