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A Quantitative Analysis of the Reliability of Aquaplast Mask Immobilization for Cranial Radiosurgery With TomoTherapy

机译:颅放射前术治疗随机疗法的血液平面掩盖固定性的定量分析

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Patient treatment setup accuracy for cranial radiosurgery (SRS) is dependent on a number of parameters; including localization and immobilization. In this study we carried out a quantitative analysis of the reliability of a radiosurgery immobilization mask system in maintaining patient position during SRS treatment sessions. Patients were fitted with a thermoplastic mask and a customized pillow designed for SRS. TomoTherapy MVCT, using 1 mm slice thickness, was carried out and the required shifts, based on bony anatomy, were applied to the patient position prior to radiotherapy. At the completion of the treatment a second MVCT was carried out to determine if any patient movement had taken place. Typical time on the treatment couch varied from 25-60 minutes. A total of 26 patients were analyzed. Some patients received more than one treatment fraction. A total of 38 MVCT measurements were included in this study. The mean absolute shift for the 38 measurements was 0.42 mm (SD=0.29) lateral, 0.75 mm (SD=0.94) longitudinal, and 0.44 mm (SD=0.42) in the vertical direction. Overall, the average vector displacement was 1.18 mm (SD=0.82). The variation in shifts between different patients was significant. Two patients had a vector shift of greater than 3.0 mm; largely due to a longitudinal displacement. Based on these results a margin of approximately 1 mm is sufficient for patient lateral and vertical motion but up to a 2 mm margin may be needed for longitudinal motion. Hence a PRV and PTV of 3 mm is required to account for patient position uncertainty. Care in the initial molding of the mask, and a customized pillow, may be key in ensuring minimal patient motion during cranial SRS.
机译:颅放射前门口(SRS)的患者治疗设置精度取决于许多参数;包括本地化和固定。在这项研究中,我们对在SRS治疗期间保持患者位置的放射外科固定掩模系统的可靠性进行了定量分析。患者配有热塑性面膜和专为SRS设计的定制枕头。在放射治疗之前,进行了使用1mm切片厚度的Tomotherapy MVCT和基于骨解剖学的所需换档施加到患者位置。在完成后,进行第二种MVCT以确定是否发生了任何患者运动。治疗的典型时间在25-60分钟内变化。共分析了26例患者。有些患者接受了多种治疗部分。本研究共纳入了38个MVCT测量。 38测量的平均绝对变换为0.42mm(SD = 0.29)横向,0.75mm(SD = 0.94)纵向,垂直方向0.44mm(SD = 0.42)。总的来说,平均载体位移为1.18毫米(SD = 0.82)。不同患者之间的变化变化显着。两名患者的矢量偏移大于3.0毫米;在很大程度上是由于纵向位移。基于这些结果,对于患者的横向和垂直运动,可能需要大约1mm的裕度,但是对于纵向运动可能需要高达2mm的余量。因此,需要3毫米的PRV和PTV来考虑患者位置不确定性。在掩模和定制枕头的初始模制中进行护理,可以是确保在颅骨时最小的患者运动的关键。

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