A case-control genome-wide association study of metabolic syndrome in Korean

摘要

Metabolic syndrome (METS) constitutes several metabolic disorders including central obesity, dyslipidemia, glucose intolerances, and elevated blood pressure. METS is known to increase the risk of developing cardiovascular disease and diabetes. Genome-wide association study (GWAS) for 2,657 cases and 5,917 controls in Korean populations was performed to discover the genetic risk factors of METS. As a result, we identified 2 SNPs with genome-wide significance level p-values(