Study of Microwave Synthesis of 2-Hydroxy phosphono acetic acid process

摘要

This research introduced microwave synthesis process of HPAA (2-hydroxyphosphonoacetic acid) which was synthesized from glyoxylate and phosphorous acid.The optimized technological conditions was defined by orthogonal experiment.The mass proportion of phosphorous and glyoxylate was 1∶1.2,catalyst mass was 1 g,95°C,25min,and itsyield rate was more than 90％.The molecular structure of product was characterized by IR spectrogram analysis.This method was simple,economical and practical.