The Implementation of Semiconductor Based Biosensors Into Point of Need Systems for the Automatized Analysis of Complex Samples

摘要

Lab on Chip systems promise compact and highly automated analysis functionality. Whenever a mobile application (Point of Need) is the purpose, also the miniaturization of the necessary infrastructure to drive the microfluidics and the read-out of the biosensor needs to be considered. This paper describes a small, mobile system that implements a Photonic Integrated Circuit (PIC) based biosensor together with a self-pumping microfluidic cartridge and all necessary infrastructure like lasers, power and control. The system's functionality was proven by performance of an ELISA assay.