首页> 外文会议>IEEE Sensors >SELF ASSEMBLED MONOLAYERS VERSUS IRON OXIDE NANOPARTICLES MODIFIED SURFACES: TWO FUNCTIONALIZATION STRATEGIES FOR FEMTOMOLAR DETECTION OF PROSTATE SPECIFIC ANTIGEN
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SELF ASSEMBLED MONOLAYERS VERSUS IRON OXIDE NANOPARTICLES MODIFIED SURFACES: TWO FUNCTIONALIZATION STRATEGIES FOR FEMTOMOLAR DETECTION OF PROSTATE SPECIFIC ANTIGEN

机译:自组装单层与氧化铁纳米粒子改性表面:前列腺特异性抗原的幻肿检测的两种功能化策略

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Two electrochemical immunosensors were investigated for prostate specific antigen detection. The first one was functionalized with 3-glycidypxypropyltrimethoxysilane self-assembled monolayer, while the second one was based on iron oxide nanoparticles functionalized with 3-aminopropyltriethoxysilane. Electrochemical impedance spectroscopy and square wave voltammetry have been investigated to follow-up the prostate specific antigen detection in a phosphate buffer solution and in a human serum. The limit of detection of both immunosensors was found of order of 10 fg/ml.
机译:研究了前列腺特异性抗原检测的两种电化学免疫转变体。第一个用3-丙啶丙基三甲氧基硅烷自组装单层官能化,而第二个是基于用3-氨基丙基三乙氧基硅烷官能化的氧化铁纳米颗粒。已经研究了电化学阻抗光谱和方波伏安法,以在磷酸盐缓冲溶液和人血清中进行后续前列腺特异性抗原检测。发现免疫传感器的检测极限为10 fg / ml。

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