ANABOLIC EFFECTS OF ULTRASOUND AS COUNTERMEASURES OF SIMULATED MICROGRAVITY IN IN-VITRO AND IN-VIVO FUNCTIONAL DISUSE MODELS

摘要

Microgravity (MG) during space flight has been known to cause adverse effect on bone quality. Data collected from studies done on spaceflights show loss of 1-1.6% bone mineral density (BMD) per space-flight-month[1] . Most BMD has been recorded in load-bearing bones [2]. Some studies has considered using drugs and different growth factors to maintain bone mass in microgravity conditions but it can be too expensive to maintain over longer periods of time besides the systematic effects of such treatments [3].