Live demonstration: A CMOS-based lab-on-chip array for combined magnetic manipulation and opto-chemical sensing

摘要

We demonstrate a CMOS-based lab-on-chip platform for combined magnetic manipulation and opto-chemical sensing. Each pixel of the 8×8 array integrates a Programmable Gate (PG) ISFET chemical sensor and an active pixel sensor, encompassed within an inductive coil. The system can be used for simultaneous optical imaging and pH sensing, and includes an auto-calibration mechanism for eliminating sensor non-idealities. Through a MATLAB-based graphical user interface, the user can program a spatiotemporal magnetic field pattern for micro-scale magnetic manipulation, in addition to visualising chemical and optical images in real time.