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Dosimetric study in the human head for CT investigation of the inner ear using the Geant4 toolkit

机译:使用Geant4工具包对人头进行内耳CT剂量学研究

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This work is a status report of the job in progress finalized to the estimation of the dose distribution inside the head of a patient undergoing a high resolution CT (Computed Tomography) for the diagnosis of pathologies related to the inner ear. Geant4 (GEometry ANd Tracking) has been used to simulate the head and propagate the particles in the human tissues. The ear has a very complex structure, in particular the inner section includes many very small structures, which are located in a very compact region (a few square centimeters), and many of them have dimensions below the millimeter. The semicircular canals and vestibule are part of the Vestibular Complex that provides the feeling of balance, rotation, gravity and linear acceleration. Otoliths, receptors in the vestibule, are small groups of calcium carbonate by the maximum diameter of 200 micrometers. Two different approaches have been checked for the representation of the human head. The first phantom has been constructed using a vector graphics approach through the geometric solids provided by Geant4. The second phantom has been constructed using an anatomical division into voxels. In particular, we achieved a volumetric model definition very close to the division into axial layers. In this approach the simulation may be customized by using DICOM CT images. In this work we will present the results obtained using the Geant4 toolkit and the suggestions we find to proceed.
机译:这项工作是正在进行中的工作的状态报告,该工作最终确定为进行高分辨率CT(计算机断层扫描)的患者头部内部剂量分布的估计,以诊断与内耳有关的病变。 Geant4(几何和跟踪)已用于模拟头部并在人体组织中传播粒子。耳朵具有非常复杂的结构,特别是内部部分包括许多非常小的结构,它们位于非常紧凑的区域(几平方厘米)中,并且其中许多的尺寸都小于毫米。半圆形管和前庭是前庭复合体的一部分,可提供平衡,旋转,重力和线性加速度的感觉。耳石是前庭中的受体,是一小群碳酸钙,最大直径为200微米。已经检查了两种不同的方法来表示人的头部。通过Geant4提供的几何实体,使用矢量图形方法构造了第一个模型。第二个幻影是使用解剖学划分为体素的方式构造的。特别是,我们获得了非常接近于划分为轴向层的体积模型定义。在这种方法中,可以通过使用DICOM CT图像来定制仿真。在这项工作中,我们将介绍使用Geant4工具包获得的结果以及我们发现要进行的建议。

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