A New Measurement to Quantity DNA Sequence and Its Application

摘要

Based on distance distribution of nucleotides in a DNA sequence, a new distance measurement, average distance of four nucleotides, was proposed. The new index can be used to describe the regularity of four nucleotides distribution in a given DNA sequence. According to the new measurement, 17 complete mammal mitochondrial genomes have been analyzed and then cluster analysis and principal component analysis have been done. The results indicate that the new measurement is an efficient index to analyze DNA sequence and organic evolution.