A study on the wall shear stress of stented artery model by using Electrochemical Technique

摘要

The stimulation of endothelial cells by the low and oscillatory arterial wall shear stress (WSS) plays a central role in restenosis. The fluid-structure interaction in the stented area alters the WSS. We have designed an in-vitro model of stented artery to study WSS within a ‘stented’ section. The experimental artery was made by casting paste silicone sealant with a Wood''s metal cast. A peristaltic pump was used to simulate a pulsatile blood flow. Electrochemical Technique was used to quantify the time-averaged WSS before and after the implantation of an independent designed stent. We obtained WSS values of about 0.6 Pa in pre-stent and post-stent regions after stenting which may provide a source of endothelial stimulation propitious to restenosis. Also, WSS of about 1.1 Pa was found in the middle of stented arterial segment after stenting which may be a less dangerous region for restenosis.