FLOW-INDUCED WALL MECHANICS OF PATIENT-SPECIFIC ANEURYSMAL CEREBRAL ARTERIES: NONLINEAR ISOTROPIC VS. ANISOTROPIC WALL STRESS

摘要

There are several biomechanical factors involved in the formation, growth, remodeling, and eventual rupture of intracranial aneurysms. In particular, hemodynamic forces have a decisive role in the biomechanical environment of the aneurysmal cerebral vasculature. Most of the previous studies on vascular mechanics assessment of intracranial aneurysms are based on idealized geometries, where it has been suggested [1] that it is highly unlikely that saccular aneurysms expand due to a limit point instability.