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Forward-looking volumetric intracardiac imaging using a fully integrated CMUT ring array

机译:使用完全集成的CMUT环形阵列的前瞻性体腔内成像

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Atrial fibrillation is the most common type of cardiac arrhythmia that now affects over 2.2 million adults in the United States alone. Currently fluoroscopy is the most common method for guiding interventional electrophysiological procedures. We are developing a 9-F forward-looking intracardiac ultrasound catheter for real-time volumetric imaging. We designed and fabricated a 64-element 10-MHz CMUT ring array with through-wafer via interconnects. We also designed custom front-end electronics to be closely integrated with the CMUT array at the tip of the catheter for improved SNR. This integrated circuit (IC) is composed of preamplifiers and protection circuitry, and can directly interface a standard imaging system. This multi-channel IC is capable of passing up to ±50-V bipolar pulses. An 8-channel front-end IC was fabricated based on this circuit topology. Additionally, a flexible PCB was designed for the integration of ring array with front-end electronics. We have acquired a PC-based real-time imaging platform and demonstrated real-time imaging with the ring array. We have also shown volume images using off-line full synthetic aperture image reconstruction method. The presented experimental results demonstrate the performance of our forward-looking volumetric intracardiac imaging approach. We are currently working on the final catheter integration and further development of our real-time imaging methods.
机译:心房颤动是心律不齐的最常见类型,仅在美国,心律失常现在已影响超过220万成年人。当前,荧光检查是指导介入电生理程序的最常用方法。我们正在开发9-F前瞻性心内超声导管,用于实时体积成像。我们设计并制造了具有直通晶圆通孔互连的64元素10MHz CMUT环形阵列。我们还设计了定制的前端电子设备,使其与导管尖端的CMUT阵列紧密集成,从而提高了SNR。该集成电路(IC)由前置放大器和保护电路组成,可以直接与标准成像系统接口。该多通道IC能够传递高达±50 V的双极性脉冲。基于这种电路拓扑结构,制造了一个8通道的前端IC。此外,还设计了一种柔性PCB,用于将环形阵列与前端电子设备集成在一起。我们已经获得了基于PC的实时成像平台,并通过环形阵列演示了实时成像。我们还显示了使用离线全合成孔径图像重建方法的体积图像。提出的实验结果证明了我们的前瞻性容积心内成像方法的性能。我们目前正在努力进行最终的导管集成,并进一步开发实时成像方法。

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