PREPARATION OF MACROPOROUS BIODEGRADABLE POLY(L-LACTIC ACID) SCAFFOLDS VIA THERMALLY INDUCED PHASE SEPARATION

摘要

The macroporous and highly-interconnected scaffold of biodegradable poly(L-lactic acid)(PLLA) in size from 10 to hundreds μm could be fabricated from the PLLA-dioxane-water ternary system via thermally induced phase separation(TIPS) in the presence of Pluronics, F-68 as a surfactant. The porous morphology was related with phase separation dynamics.