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The oral route: a wealth of drug delivery opportunities

机译:口服途径:大量的药物输送机会

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摘要

Now more than ever, drug delivery scientists are challenged with a wealth of opportunities in developing innovative drug delivery systems for oral administration. The impetus for this is three-fold: (a) the recognition of a need to develop an orally bioavailable formulation in a timely fashion, (b) the avalanche of drug candidates made possible by high throughput drug discovery paradigms, and (c) a better understanding of the interplay of polymer chemistry and cell biology in the design of an oral drug delivery sy6stem that meets the needs of peptide and protein drugs.
机译:如今,药物研发科学家面临着比以往更多的挑战,他们需要开发创新的口服药物给药系统。其推动力来自三方面:(a)认识到需要及时开发口服生物利用型制剂,(b)高通量药物发现范例使可能的候选药物雪崩,以及(c)a在设计满足肽和蛋白质药物需求的口服药物输送系统时,可以更好地理解高分子化学和细胞生物学之间的相互作用。

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