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Disease risks of traffic noise - a large case-control study based on secondary data

机译:交通噪声的疾病风险 - 基于辅助数据的大案例控制研究

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Background: Several studies point to an elevated risk for cardiovascular disease induced by traffic noise. Evidence is limited with respect to depressive disorders and breast cancer. Objective: To examine the association between aircraft noise, road traffic and railway traffic noise with cardiovascular diseases (myocardial infarction, stroke, heart failure or hypertensive heart disease), depressive episodes and breast cancer in a large case-control study. Methods: The classification of cases (diagnosed 2006-2010) and control subjects was based on insurance claims and prescription data provided by three large statutory health insurance funds in the Rhine-Main area (administrative region Darmstadt, Rhine Hesse). For all insured individuals (1,026,670 people aged 40 years or more), address-specific exposure to aircraft, road and railway traffic noise in 2005 was estimated. Odds Ratios (OR) were calculated using logistic regression analysis, adjusted for age, sex, local proportion of persons receiving unemployment benefits, and individual socioeconomic status (when available). Results: Overall, results of our case-control study suggest a relationship between traffic noise exposure and the pathogenesis of myocardial infarction, stroke, heart failure and unipolar depression.
机译:背景:几项研究指出交通噪音诱导的心血管疾病的升高风险。关于抑郁症和乳腺癌的证据是有限的。目的:审查飞机噪声,道路交通和铁路交通噪声与心血管疾病(心肌梗死,中风,心力衰竭或高血压),抑郁发作和乳腺癌在大型案例对照研究中的关系。方法:案件的分类(诊断为2006-2010)和控制受试者是基于莱茵 - 主要区域(行政区域Darmstadt,Rhine Hesse)的三个大法定健康保险基金提供的保险索赔和处方数据。对于所有被保险人(4026,670人或更长时间)的所有被保险人(1,026,670人),估计了2005年的地址特定于飞机,道路和铁路交通噪音。使用Logistic回归分析计算ODDS比率(或),调整为年龄,性别,接受失业福利的人和个人社会经济地位(可用时)的年龄,性别比例。结果:总体而言,我们的案例对照研究的结果表明交通噪声暴露与心肌梗死,中风,心力衰竭和单极抑郁症之间的关系。

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