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Detecting Chronic Diseases from Sleep-Wake Behaviour and Clinical Features

机译:从睡眠觉醒行为和临床特征检测慢性疾病

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Many chronic diseases show evidence of correlations with sleep-wake behaviour, and there is an increasing interest in making use of such correlations for early warning systems. This research presents an approach towards early chronic disease detection by mining sleep-wake measurements using deep learning. Specifically, a Long-Short-Term-Memory network is applied on actigraph data enriched with clinical history of patients. Experiments and analysis are performed targeting detection at an early and advanced disease stage based on different clinical data features. The results show for disease detection an averaged accuracy of 0.62, 0.73, 0.81, 0.77 for hypertension, diabetes, sleep apnea and chronic kidney disease, respectively. Early detection performs with an averaged accuracy of 0.49 for sleep apnea and 0.56 for diabetes. Nevertheless, compared to existing work, our approach shows an improvement in performance and demonstrates that predicting chronic diseases from sleep-wake behavior is feasible, though further investigation will be needed for early prediction.
机译:许多慢性疾病显示出与睡眠-觉醒行为相关的证据,并且越来越多的兴趣将这种相关性用于预警系统。这项研究提出了一种通过使用深度学习挖掘睡眠/唤醒测量值来进行早期慢性疾病检测的方法。具体而言,将长时记忆网络应用于充实了患者临床病史的活动记录仪数据。根据不同的临床数据特征,在疾病的早期和晚期阶段进行针对目标检测的实验和分析。结果表明,对于疾病,高血压,糖尿病,睡眠呼吸暂停和慢性肾脏病,疾病检测的平均准确度分别为0.62、0.73、0.81、0.77。进行早期检测时,睡眠呼吸暂停的平均准确度为0.49,糖尿病患者的平均准确度为0.56。尽管如此,与现有工作相比,我们的方法显示出性能上的改进,并表明从睡眠觉醒行为预测慢性疾病是可行的,尽管早期的预测仍需要进一步的研究。

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