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Identification of Genes Encoding Receptors for Six Pseudomonas aeruginosa Phages

机译:鉴定铜绿假单胞菌六个噬菌体受体的基因

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Pseudomonas aeruginosa is one of the main pathogens of nosocomial infection, due to the ever increasing occurrence of multidrug resistant clinical isolates, there is an urgent need for development of new types of antimicrobial agents [1]. Phages can specifically lyse host bacterial cells, and can be used as alternatives to antibiotics. Phage therapy has been practiced in the control of P. aeruginosa infection for 50 years, and some animal experiments have confirmed the effectiveness of the relevant phage therapies [2-5].
机译:铜绿假单胞菌是医院感染的主要病原体之一,由于耐多药临床分离株的发生率不断增加,迫切需要开发新型的抗菌剂[1]。噬菌体可以特异性裂解宿主细菌细胞,并且可以用作抗生素的替代品。噬菌体疗法已经在控制铜绿假单胞菌感染中实践了50年,一些动物实验已经证实了相关噬菌体疗法的有效性[2-5]。

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