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Gene Expression of Macrophage Phenotype Profile Regulated by Different Matrices

机译:不同基质调控巨噬细胞表型谱的基因表达

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Conclusions: Synthetic meshes activated proinflammatory cytokine (Ml) genes while biologic materail up-regulated genes related to anti-inflammation (M2) phenotype macrophage. These results demonstrated that subtype of inflammation was accurately represented by gene expression profiles and con-elated well to representative histological and immunostaining staining around the mesh.
机译:结论:合成网激活了促炎细胞因子(M1)基因,而生物材料上调了与抗炎(M2)表型巨噬细胞有关的基因。这些结果表明,炎症亚型由基因表达谱准确地表示,并与网状组织的代表性组织学染色和免疫染色良好相关。

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