The efficacy of using RGD peptide sequence on in vitro wound healing

摘要

In scientific area, many different studies are carried out to ensure the development of more effective and rapid wound healing method. Applied and developed several methods aims rapid wound healing with minimal discomfort to the patient which is also allow the movement of epithelial cells and to allow the regeneration of cells during to wound healing process with provided the ideal environment. It is known that RGD peptide sequences can support cell regeneration and increase cell adhesion by activating integrins therewithal synthesis of the peptide sequence simple and low cost, research in this field has gained momentum in recent years. The present study examined the effect of culture medium contain peptide sequence with concentration of 0.1 mg/ml and 0.5 mg/ml, on an in vitro wound healing model using by L929 fibroblast cells.