首页> 外文会议>International conference on frontier computing: theory, technologies and applications >Constructing Prediction Model of Lung Cancer Treatment Survival
【24h】

Constructing Prediction Model of Lung Cancer Treatment Survival

机译:构建肺癌治疗保存预测模型

获取原文

摘要

According to statistics of the Ministry of Health and Welfare (Taiwan) in 2016, the first of Top Ten causes of death was cancer. In this category, percentages of trachea, bronchus and lung cancer were the highest. Thus, it is particularly important to study the disease. Coverage rate of national health insurance in Taiwan is up to 99.6%. Database of the national health insurance includes insurance information of the public. It is currently the mostly complete, mature and continuous clinical medial empirical data. With precise data and sufficient samples, they become the most appropriate and precise data for prediction of effectiveness of clinical illness treatment and comorbidity analysis. This study focuses on non-small cell lung cancer. It obtains cancer registration files from two million files in database of national health insurance, and screens patients who have suffered from ICD C33-34 "trachea, bronchus and lung cancer". It then connects with OPDTE of outpatient services of national health insurance to include factors of comorbidity of disease in model design and treat DEATH as analytical figure after treatment and prognosis. By linear and nonlinear data mining, it studies effects of different therapies on survival rate of lung cancer patients in three years and establishes prediction model. Through Artificial Neural Network (ANN) and Logistic Regression (LR), this study successfully establishes prediction model of survival rate of treatment of non-small cell lung cancer. When the best point of LR model: Sensitivity = 77.3 and Specificity = 73.8, it includes 81% (AUROC, Area Under ROC curve) of model precision rate. When the best point of ANN model: Sensitivity = 77.6 and Specificity = 76.8, it can include 83% (AUROC) model precision rate. It shows that model precision rate of ANN is higher than logistic regression model.
机译:根据卫生和福利部(台湾)的统计数据,2016年,前十大死亡原因是癌症。在此类别中,气管,支气管和肺癌的百分比最高。因此,研究疾病尤为重要。台湾国民健康保险的覆盖率高达99.6%。国家健康保险数据库包括公众的保险信息。它目前是主要完整,成熟和持续的临床内心经验数据。具有精确的数据和足够的样品,它们成为最合适和精确的数据,用于预测临床疾病治疗和合并症分析的有效性。本研究重点是非小细胞肺癌。它从国民健康保险数据库中获得200万张文件的癌症登记档案,以及患有ICD C33-34“气管,支气管和肺癌”的筛选患者。然后,与国家医疗保险的门诊服务OPDTE连接,包括在治疗和预后后的模型设计和治疗死亡中疾病的合并症因素。通过线性和非线性数据挖掘,IT研究不同疗法对三年肺癌患者存活率的影响,建立预测模型。通过人工神经网络(ANN)和Logistic回归(LR),本研究成功地建立了非小细胞肺癌治疗的存活率预测模型。当LR模型的最佳点:灵敏度= 77.3和特异性= 73.8时,它包括模型精密率的81%(AUROC,ROC曲线下的区域)。当ANN模型的最佳点:灵敏度= 77.6和特异性= 76.8,它可以包括83%(AUROC)模型精度率。它表明,ANN的模型精度率高于Logistic回归模型。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号