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Reduced variability in pulse wave velocity in depressed patients with suicidal ideation

机译:降低具有自杀意念的抑郁症患者的脉搏波速度变异性

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Recently arterial stiffness was found to be associated with depression. The aim of this study was to investigate the association between arterial pulse wave velocity (PWV) and Major Depressive Disorder (MDD) with or without suicidal ideation. Twenty unmedicated MDD patients with a history of suicidal ideations (Age: 32.37??9.53 years) and 20 unmedicated MDD patients without any history of suicidal ideations (Age: 36.84??8.66) were recruited for this study at a psychiatric clinic in the UAE. Depression severity was assessed with the Hamilton Depression Rating Scale and the Beck Depression Inventory. Pulse wave velocity (PWV) was estimated from the ratio of half of the height and Pulse Transit Time which is defined as the time delay between the R-wave of the ECG and the arrival of the pulse wave in the index finger respectively. MDD Patients with suicidal ideation were found to have reduced low frequency (LF) and high frequency (HF) power of PWV compared to MDD patients without suicidal ideations. Suicidal score was negatively correlated (r=???0.54;p
机译:最近发现动脉僵硬与抑郁症有关。这项研究的目的是调查有或没有自杀意念的动脉脉搏波速度(PWV)与严重抑郁症(MDD)之间的关联。在阿联酋的一家精神病学诊所招募了20名具有自杀意识史的未药物治疗的MDD患者(年龄:32.37-9.53岁)和20名无自杀意识史的未药物治疗的MDD患者(年龄:36.84-8.66)。 。用汉密尔顿抑郁量表和贝克抑郁量表评估抑郁的严重程度。脉搏波速度(PWV)是根据高度的一半与脉搏传播时间的比率估算的,该时间分别定义为ECG的R波和食指到达脉搏波之间的时间延迟。与没有自杀观念的MDD患者相比,具有自杀意念的MDD患者的PWV低频(LF)和高频(HF)功率降低。自杀得分呈负相关(r = ??? 0.54; p

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