Complexity of cerebral blood flow velocity and arterial blood pressure in subarachnoid hemorrhage using time-frequency analysis

摘要

We investigated changes of time-frequency (TF) complexity, in terms of Rényi entropy and a measure of concentration, of middle cerebral blood flow velocity (CBFV) and arterial blood pressure in relation to the development of cerebral vasospasm in 15 patients after aneurysmal subarachnoid hemorrhage. Interhemispheric differences in the period of no vasospasm and vasospasm were also compared. Results show reduced complexity of TF representations of CBFV on the side of aneurysm before vasospasm was identified. This potentially can serve as an early-warning indicator of future derangement of cerebral circulation.