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Toward complex multipolar selective neural stimulation

机译:走向复杂的多极选择性神经刺激

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We introduce a new approach for the investigation of multipolar selective neural stimulation. We aim at comparing existing solutions from the literature and innovate in this field with advanced strategies. We have developed a multichannel stimulator, Stim'ND, which allows us to control independently the parameters of complex stimulation profiles of 12 channels for a large number of stimulating current configurations. In this paper, we present preliminary experimental results on a multi-contact cuff electrode, placed around the sciatic nerve of a rabbit 4 multipolar stimulation configurations have been tested and the achieved selectivity in terms of muscle activation investigated. The results are in accordance with the literature and enable us to validate our approach from theoretical and technological points of view. Furthermore the stimulator was designed following the norms and rules that apply to human active implantable medical device so that the technology is currently approved to be transferred to human trials.
机译:我们介绍了一种研究多极选择性神经刺激的新方法。我们旨在比较现有文献中的解决方案,并通过先进的策略在这一领域进行创新。我们已经开发了一种多通道刺激器Stim'ND,它使我们能够针对大量刺激电流配置独立控制12个通道的复杂刺激曲线的参数。在本文中,我们介绍了在兔坐骨神经周围放置的多触点袖带电极上的初步实验结果,对4种多极刺激配置进行了测试,并研究了在肌肉激活方面达到的选择性。结果与文献一致,使我们能够从理论和技术角度验证我们的方法。此外,刺激器是按照适用于人类有源植入式医疗设备的规范和规则设计的,因此该技术目前已被批准用于人体试验。

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