A continuous counter current extraction process for there extraction of hydrocortisone from the fermentation liquor has been developed with 12 mM/L HP-(3-CD. The distribution ratios of hydrocortisone increased with increasing temperature, the distribution was also affected by the ammonium sulfide content, the greater flow rate and the amount of organic phase, the less theoretical stages of extraction theory series was performed under the other operation condition. When the hydrocortisone was extracted from the fermentation liquor with the butylacetate, the distribution ratio reduced with the increasing of high concentration of the hydrocortisone. The recovery of hydrocortisone and epi-hydrocortisone through the extraction process was 98.8% with a flow ratio of 1 and 6 stages.
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机译：从发酵液中提取氢化碳酮的连续计量响应电流萃取方法已开发为12mm / L HP-（3-CD。随着温度的增加而增加氢化胞质的分布比，分布也受硫化氢含量的影响，流速和有机相的量，在其他操作条件下进行萃取理论系列的理论阶段越少。当从用丁酯中萃取氢化液，随着高的增加，分配比率降低氢化胞质浓度。通过提取过程的氢化胞松子和外液体鞘酮的回收率为98.8％，流量比为1和6阶段。
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