Microtextured Surface to Deter Biofilm Related Orthopedic Implant Infections - A Preliminary Study

摘要

The data has suggested there is an optimal topographical geometry that will deter biofilm formation while encouraging cellular attachment. Further in vitro studies are needed to optimize the geometrical design. This would help develop novel solutions to biofilm-related orthopaedic infections. Future studies will investigate the laser etching fabrication technique to create patterns on curved titanium surfaces. An early prosthetic infection model will also be created to test the ability of an intramedullary implant with the optimized microtextured surface to deter biofilm formation in vivo and, subsequently, prevent implant-related infections from occurring.