Identification of brain networks using time-varying spatial constraints of neural activity reconstruction

摘要

Electroencephalographic (EEG) data give a direct non-invasive measurement of neural brain activity. Nevertheless, the common assumption about EEG stationarity (timeinvariant process) is a strong limitation for understanding real behavior of underlying neural networks. Here, we propose an approach for finding networks of brain regions connected by functional associations (functional connectivity) that vary along the time. To this end, we compute a set of a priori spatial dictionaries that represent brain areas with similar temporal stochastic dynamics, and then, we model relationship between areas as a time-varying process. We test our approach in both simulated and real EEG data where results show that inherent interpretability provided by the time-varying process can be useful to describe underlying neural networks.