Chapter 66 Observation of Curative Effect on 200 Cases of Myasthenia Gravis Treated with Traditional Chinese Medicine

摘要

Aim: To observe the curative effect of applying a patented traditional Chinese medicine, namely "a traditional Chinese medicine for treating myasthenia gravis" (assigned Chinese Patent of Invention in 2007), to myasthenia gravis. Methods: 200 cases of myasthenia gravis were collected during 1988-2010. One single course of treatment takes 3 months when using the above-mentioned patented medicine. Such changes of clinical symptoms are noticed before and after treatment: eyelid ptosis, diplopia, weakness, dysarthria, dysphagia, choke cough. We compile scorings according to the quantitative myasthenia gravis (QMG) score . system of Myasthenia Gravis Foundation of America. Curative effect: (1) Short-term: the shortest treatment course of this group of cases was 1 month and the longest was 30 months with an normal distribution of 7.21 ± 6.23 months. Among the 200 cases, 104 cases were fully recovered (52 %), 58 cases had obvious effect (29 %), 31 cases (15.5 %) were effective and 7 cases were ineffective (3.5 %), hence the total effective rate was 96.5 % (Table 66.1 in the text). There is a huge difference (P ＜ 0.001, Table 66.2 in the text) between QMG scores of various symptoms before and after treatment (paired-t test). (2) Long-term curative effect: through following up part of the recovered patients (24 cases) for at least half a year and at most 19 years with an average period of 5.72 years, the patients can still participate in normal work or housework without recurrence. Conclusion: The curative effect of 200 cases of myasthenia gravis treated by this patent traditional Chinese medicine was satisfied during 1988-2010.