Self-assembly polymer-protein nanogels modulate immune response through polymer-mediated adjuvant effects

摘要

Conclusion:"We report"that the pHEMA nanogel system promotes a robust immune response, as measured by flow cytometry of lymphoid tissues. We additionally demonstrate the TLR possibly responsible for its immunogenicity. Future ongoing work will focus on testing immunogenicity in MYD88 knockout mice as well will use an infectious disease antigen.