The effect of different sterilization techniques on material characteristics of a biodegradable nanocomposite polymer for use in tissue engineering purposes and its in-vitro and in-vivo biocompatibility

摘要

This study demonstrates sterilization-induced changes in material properties of our novel biodegradable polymer platform. In vitro and in vivo results showed promising biocompatibility profiles which are fundamentally important for clinical translation of any implantable devices. For future studies, the skin regeneration potential of this novel biomaterial shall be evaluated and optimized.