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Miniaturized optical-fiber endoscope without inertial scan for simultaneous imaging and laser microsurgery

机译:无需惯性扫描的微型光纤内窥镜,可同时进行成像和激光显微手术

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Minimally invasive surgery benefits from small-sized, multi-purpose endoscopic devices. To this end, a single-fiber-based optical concept performing simultaneous, spectrally encoded, inertial-free, confocal microscopy and high-precision laser microsurgery (SECOMM) was recently demonstrated. SECOMM achieves a 2D spatial dispersion by the use of a virtually imaged phased array (VIPA) spectral disperser, in conjunction with a reflective diffraction grating, creating a one-to-one mapping between spatial coordinates and optical wavelength. In this contribution we review a highly miniaturized, axial, 2D spatial disperser design, also based on a VIPA, but together with a perpendicularly aligned volume holographic grating embedded between two prisms (GRISM). This combination produces a 2D-angular dispersion often referred to as spectral shower. We specifically consider a tissue-ablation-friendly 800 nm center wavelength, with a 20 nm pulse bandwidth representing a Ti:sapphire pulsed laser light source. Our endoscope design can, however, also operate at other wavelengths such as visible and infrared. We first theoretically investigate the spectral shower in angular units and provide a parameter analysis for the proposed axial design. Second, we concentrate on the crucial part of light coupling into the spectral disperser. With respect to the underlying center wavelength and bandwidth, and to our theoretical findings, we exemplarily show an optimized device that supports a 50 × 50 pixel resolution at a device diameter as small as 3.6 mm.
机译:微创手术得益于小型,多功能内窥镜设备。为此,最近展示了一种基于单纤维的光学概念,该概念可以同时进行光谱编码,无惯性,共聚焦显微镜和高精度激光显微外科手术(SECOMM)。 SECOMM通过使用虚拟成像相控阵(VIPA)光谱分散器和反射衍射光栅,实现了二维空间色散,从而在空间坐标和光波长之间建立了一对一的映射。在本文中,我们回顾了同样基于VIPA的高度小型化的轴向二维空间分散器设计,以及嵌入在两个棱镜之间的垂直对齐的体积全息光栅(GRISM)。这种组合会产生2D角色散,通常称为频谱喷淋。我们特别考虑了组织消融友好的800 nm中心波长,其中20 nm的脉冲带宽代表了Ti:蓝宝石脉冲激光光源。但是,我们的内窥镜设计也可以在其他波长下工作,例如可见光和红外光。我们首先在理论上研究以角度为单位的频谱喷淋,并为提出的轴向设计提供参数分析。其次,我们专注于光耦合到光谱分散器中的关键部分。关于潜在的中心波长和带宽以及我们的理论发现,我们示例性地显示了一种优化的设备,该设备在小至3.6 mm的设备直径下支持50×50像素的分辨率。

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