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Optical simulation environment with accurate gamma photon penetration model for PET detector blocks

机译:光学仿真环境,具有用于PET探测器块的精确伽​​马光子穿透模型

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Positron Emission Tomography (PET) is a widely used nuclear medical imaging technique that provides functional information of human organs. In the PET device the detector plays an important role. It stops the gamma photons and generates an electronic signal which is processed by the detector system electronics. The geometrical and optical properties of the detector block have fundamental influence on the basic characteristics of a given PET device. Accurate detector block design is required to achieve appropriate system sensitivity and detector crystal needle identifiability. In our previous work we have created and validated a DETECT2000 based modelling environment, called PetDetSim, able to simulate and analyze different PET detector block geometries. PetDetSim models the gamma photon penetration in a simplified way. This simplification significantly reduced the simulation time but sometimes leaded to inaccurate result. Consequently, a better gamma photon penetration technique should be adopted in order to provide a more precise/realistic detector response as inter-crystal scattering can lead to mispositioning detected events and can complicate calibration of PET detectors. In this work we have extended our environment with a precise gamma photon penetration model using the Geant4 based GATE simulation toolkit. The result of extending the simulation environment with GATE simulation resulted in “noise” in the detector response originating from inter-crystal scattering. The result is a more realistic PET detector response that can be simulated with our environment in order to support the development of novel detector block designs and energy- and position-discrimination algorithms.
机译:正电子发射断层扫描(PET)是一种广泛使用的核医学成像技术,可提供人体器官的功能信息。在PET设备中,检测器起着重要的作用。它停止伽马光子,并产生一个电子信号,该信号由探测器系统的电子设备处理。检测器块的几何和光学特性对给定的PET设备的基本特性有根本的影响。需要正确的检测器模块设计,以实现适当的系统灵敏度和检测器晶体针的可识别性。在我们之前的工作中,我们创建并验证了基于DETECT2000的建模环境PetDetSim,该环境能够模拟和分析不同的PET检测器块几何形状。 PetDetSim以简化的方式对伽马光子穿透进行建模。这种简化大大减少了仿真时间,但有时会导致结果不准确。因此,应采用更好的伽马光子穿透技术,以提供更精确/逼真的检测器响应,因为晶间散射会导致错误定位检测到的事件并使PET检测器的校准复杂化。在这项工作中,我们使用了基于Geant4的GATE仿真工具包,通过精确的伽马光子穿透模型扩展了我们的环境。用GATE模拟扩展模拟环境的结果导致检测器响应中的“噪声”源自晶间散射。结果是可以在我们的环境中模拟出更逼真的PET检测器响应,以支持新型检测器模块设计以及能量和位置区分算法的开发。

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