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Fabrication of a Carbon Chain Based Nanosensor for Maximizing Spatial Resolution in DNA Sequencing

机译:基于碳链的纳米传感器制备用于使DNA测序中的空间分辨率最大化

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Using a carbon chain as the sensing element can significantly improve the spatial resolution in nanodevice based single molecule DNA sequencing. In this report, we demonstrate a top-down approach to reduce a single monolayer graphene attached to a silicon microelectrode chip to a sub-nanometer wide carbon chain suitable for DNA sequencing. This approach consists three major processing steps to first transfer the graphene to the chip, dice the attached graphene into graphene nanoribbons using Focused Ion Beam (FIB), and finally reduce the ribbon width by knocking off carbon atoms on the ribbon edge using Transmission Electron Microscopy (TEM). A final carbon chain of 0.8 nm wide and 5 nm long is accomplished. The measured electrical properties of the reduced graphene agree well with previous studies.
机译:用碳链作为传感元件可以显着提高基于纳米分子的单分子DNA测序中的空间分辨率。在本报告中,我们证明了一种自上而下的方法,以减少连接到硅微电极芯片的单个单层石墨烯,以适合于DNA测序的亚纳米宽碳链。该方法包括三个主要的处理步骤首先将石墨烯转移到芯片上,使用聚焦离子束(FIB)将附着的石墨烯骰子进入石墨烯纳米,并且最终通过透射电子显微镜敲掉带状边缘上的碳原子来减少带状宽度(TEM)。完成最终的碳链和5nm长的碳链。降低石墨烯的测量电性能与先前的研究一致。

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