Biomimetic hydroxyapatite-collagen biocomposite scaffold for bone tissue engineering

摘要

A collagenano-HA composite scaffold has been developed by a biomimetic precipitation method. This method is able to precipitate nano-HA crystallites within the collagen fibril matrix. Randomly aligned collagen fibrils would guide HA nano-crystallites precipitation and growth, resulted a nearly untextured structure. Such composite scaffold may be an appropriate substrate for bone tissue engineering.